TYPBAR TCV VIAL

Typbar TCV is a Typhoid Vi Conjugate vaccine used to protect against typhoid fever, caused by Salmonella Typhi bacteria. This vaccine is particularly important for individuals traveling to or living in areas where typhoid fever is common. The vaccine contains Vi capsular polysaccharide of Salmonella Conjugated to  Tetanus Toxoid carrier protein. It is WHO and IAP Prequalified vaccine.Conjugated to TT protein antigen  

How It Works

Typbar TCV  contains inactivated components of the Salmonella Typhi bacteria, which stimulate the immune system to develop protection against the disease without causing illness. It does not offer protection against infection  caused by salmonella para typhi or non typhoid salmonellas.Protection is not 100%. Protection starts in 2-3 weeks post vaccination.Serological Protection is T cell dependent. Plain Vi Polysaccharide (Non Conjugated Typhoid vaccines don’t elicit T cell response.  

Administration

• Given as a single injection, usually in the upper arm(Deltoid, >2 yrs)  or Anterolateral thigh (till 2 yrs)
• Recommended for individuals aged >6 months and older till 65 yrs, especially those traveling to endemic areas.

Doses

• Doses: Single dose. Booster after 3 yrs of Primary vaccination can be given to people who are at risk of typhoid fever

Side Effects

Common side effects may include:

• Pain or swelling at the injection site
• Mild fever
• Headache
• Fatigue

Severe reactions are rare.

Pregnancy and Lactation

• Pregnancy: Not to be given.Should be discussed with a healthcare provider to weigh risks and benefits.
• Lactation: Not to be given.Generally considered safe, but consult with a healthcare provider.

Minimum Age Group

• Minimum Age: Approved for use in individuals aged >6 months to 65 years.

Contraindications

• Allergic Reactions: Not for individuals with severe allergies to any component of the vaccine.
• Severe Illness: Vaccination should be postponed in cases of acute, severe febrile illness.

Typbar TCV  is essential for preventing typhoid fever, especially for travelers and those in endemic areas. Always consult healthcare providers for personalized advice and recommendations.