pentavac pfs

Pentavac  is a combination vaccine that provides protection against Five serious diseases: diphtheria, tetanus, w-pertussis (whooping cough), hepatitis B and Haemophilus influenzae type b (Hib). This vaccine is commonly used in pediatric immunization programs to ensure comprehensive protection with fewer injections.

How It Works

Hexasil contains inactivated components of the bacteria and viruses that cause these diseases, stimulating the immune system to develop immunity without causing the actual diseases.

Administration

• Primary Series: Given as a series of three injections starting at 6 weeks of age, with a minimum interval of 1 month(4 wk) between each dose.WHO recommends 6.10,14 wk as Primary Schedule.Interval can vary between 4-8 wk between primary vaccines.
• Booster: Administered at least 6 months after the last primary dose, typically between 12-15 months of age or 12-23 months of age.
• Alternate Schedules: If hepatitis B is given at birth, the primary schedule can be at 6, 10, and 14 weeks, with boosters following the same schedule.
• Administered intramuscularly, usually in the upper thigh for infants (alternating thighs).
• Since IPV is compulsory at 6,10,14 wks, 18 months & 4 yrs, and separate IPV injection is not available in India, so Pentavac should not be given for Primary Vaccination and Boosters (both 18 months and 4 yrs)

Side Effects

Common side effects may include:

• Pain or swelling at the injection site
• Fever
• Irritability
• Loss of appetite
• Fatigue

Severe reactions are rare.

Pregnancy and Lactation

• Pregnancy: Not applicable, as it is intended for infants and young children.
• Lactation: Not applicable.Safe for nursing mothers to administer to their infants.

Efficacy Studies

• Long-Term Protection: Studies have shown that Hexasil provides long-lasting protection against all Five diseases, with close to 100% seroprotection observed by 9 yrs of age.

Minimum Age Group

• Minimum Age: Approved for use in infants starting at 6 weeks old.
• Maximum Age: Recommended for children up to 2 years old.

Contraindications

• Allergic Reactions: Not for individuals with severe allergies to any component of the vaccine.
• Severe Illness: Vaccination should be postponed in cases of acute, severe febrile illness, history of febrile convulsions.

Pentavac is an essential part of the routine immunization schedule for infants, providing comprehensive protection against six serious diseases with fewer injections. Always consult healthcare providers for detailed vaccination schedules and personalized recommendations.