VARIL RIX

Varilrix Vaccine

Varilrixis a vaccine used to protect against varicella (commonly known as chickenpox), a highly contagious disease caused by the varicella-zoster virus. Chickenpox typically causes an itchy rash and flu-like symptoms and can lead to severe complications, particularly in infants, adults, and individuals with weakened immune systems. Vaccination with Varilix significantly reduces the risk of developing chickenpox and its associated complications.

How It Works

Varilrix contains a live, attenuated strain of the varicella-zoster virus (Oka strain). The virus in the vaccine has been weakened so that it cannot cause the disease in healthy individuals but is still able to stimulate the immune system to develop long-lasting immunity against chickenpox.

Administration

• Dosage: Varilrix is typically administered in a two-dose series.
•  Schedule: Typically administered in two doses > 12 month age- 12 yr,2 doses-3 month apart.> 12 yr-2 doses 4-8 wk apart.
• Can be given <50 yrs if no past history of chickenpox.
• Administration Method: The vaccine is given as a subcutaneous injection, usually in the upper arm.

Side Effects

Common side effects may include:

• Redness, pain, or swelling at the injection site
• Mild fever
• Rash similar to mild chickenpox
• Irritability

Serious side effects are rare but may include allergic reactions.

Pregnancy and Lactation

• Pregnancy: Varilrix is contraindicated in pregnancy. Women should avoid becoming pregnant for at least one month after receiving the vaccine.
• Lactation: There is limited data on the use of Varilix during lactation; consult a healthcare provider for advice.

Age Group

• Minimum Age: Approved for use in children starting at 12 months old.
• Upper Age Limit: The vaccine can be administered to susceptible individuals of any age, including adults who have not had chickenpox or have not been vaccinated.

Contraindications

• Allergic Reactions: Not recommended for individuals with severe allergies to any component of the vaccine.
• Immunocompromised Individuals: Should not be given to individuals with weakened immune systems, such as those undergoing chemotherapy or with severe immune deficiencies.
• Pregnancy: Contraindicated during pregnancy.

Nature of Antigen

• Nature of Antigen: Varilrix contains the live, attenuated Oka strain of the varicella-zoster virus.

Vaccine Type

• Type: Varilix is a monovalent vaccine, targeting the varicella-zoster virus alone.

Origin and Manufacturer

• Origin: Varilrix is an imported vaccine.
• Manufacturer: The vaccine is produced by GlaxoSmithKline (GSK), a global healthcare company.
• Introduction Year: Varilrix was introduced in 1994.

Varilrixis an effective tool in preventing chickenpox and its complications, offering protection for both children and adults who have not yet been exposed to the virus. Always consult a healthcare provider for personalized vaccination advice and to determine the appropriate schedule for Varilix.